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It is difficult to tell. Like all disease processes there can be a natural waxing and waning that can be unpredictable at times. This can be minimalized by taking the appropriate medications, as well as being compliant with taking those medications. Has he been compliant with taking his medications, as people with schizophrenia and schizoaffective disorder have a high incidence of non-compliance. If he engages in activity currently in which he is either a danger to himself or others, he should see his perscriber or go to the emergency room immediately. With his change in behavior that is troublesome, it would be best for him to see his prescriber as soon as possible. Although it is not a guarantee, the earlier that problems are seen such as this, usually the greater the chance of having effective early and successful intervention.