Hi jac and thanks for using Justanswer.com
Yes except for the klonopin there is no reason he cannot operate a motor vehicle or any other kind of machinery without a problem. The only issue is the klonopin and that should be prescribed and taken separately from the other medications that you listed.
No worries. None of the other medications would cause a problem.
Best wishes and warmest regards XXXXX XXXXX Cathy