How JustAnswer Works:

  • Ask an Expert
    Experts are full of valuable knowledge and are ready to help with any question. Credentials confirmed by a Fortune 500 verification firm.
  • Get a Professional Answer
    Via email, text message, or notification as you wait on our site.
    Ask follow up questions if you need to.
  • 100% Satisfaction Guarantee
    Rate the answer you receive.

Ask Dr. Steve Your Own Question

Dr. Steve
Dr. Steve, Psychologist
Category: Mental Health
Satisfied Customers: 370
Experience:  19 years conducting therapy; book author; newspaper columnist; former co-host of radio show
Type Your Mental Health Question Here...
Dr. Steve is online now
A new question is answered every 9 seconds

Can long term use of serterline cause psycosis and delusio

Resolved Question:

Can long term use of serterline cause psycosis and delusions
Submitted: 4 years ago.
Category: Mental Health
Expert:  Dr. Steve replied 4 years ago.
Hi johanne:

(I am assuming you meant to write "sertraline")

In general, no. Typically, psychosis and delusions are associated with the dopamine systems of the brain, and sertraline affects only the serotonin systems. If a person were to withdraw suddenly, a major depressive episode can be triggered (which can, albeit extremely rarely, include some psychotic symptoms - this would not be permanent, however).

To answer your question directly, long term usage in and of itself should not cause psychosis or delusions.

Thanks!

Dr. Steve

Customer: replied 4 years ago.
is there any combination of drugs taken with this drug that can cause psycosis/delusions since my father has desplayed irrational behavour during the last year stating for instance that I was not his daughter and I am aged 48, This together with accusations of me speeding rumours of him having sex with animals and prostitutes.
Expert:  Dr. Steve replied 4 years ago.

Hi Joanne:

Let's take the sertraline out of the equation for a minute. If he is taking other drugs in a "cocktail" format, they could be creating an interaction effect that would affect dopamine levels. Combined with his advancing age, the number of combinations is endless, and takes me out of my knowledge base. My recommendation to you would be to gather his records/prescriptions from all of his doctors and present them to the doctor with whom you feel most comfortable or with whom he has the best relationship. Too, s/he should be familiar with the changing neurochemistry of the aging brain. It will be that physician's responsibility then to trouble-shoot the potential interaction effects.

But it bears repeating, the sertraline will not impact the systems that would be responsible for the paranoia and delusions. I would include it in the list given to his doctor, but invest more energy in examining other interactions.

It is also possible (unfortunately) that your father is suffering from advancing dementia. At his age, it would not be common, but not impossible, either. A positive family history for Alzheimer's or dementia would raise a red flag, as would if your father has been forgetting little things for the past few years. Still, to be this floridly paranoid would discount an acute onset - in other words, he would not get to this point quickly. His condition would have deteriorated slowly over the course of a few years. A fast onset almost invariably points to medications.

A geriatric psychiatrist would be the source for this knowledge.

Thanks!

Dr. Steve

Dr. Steve, Psychologist
Category: Mental Health
Satisfied Customers: 370
Experience: 19 years conducting therapy; book author; newspaper columnist; former co-host of radio show
Dr. Steve and 3 other Mental Health Specialists are ready to help you

JustAnswer in the News:

 
 
 
Ask-a-doc Web sites: If you've got a quick question, you can try to get an answer from sites that say they have various specialists on hand to give quick answers... Justanswer.com.
JustAnswer.com...has seen a spike since October in legal questions from readers about layoffs, unemployment and severance.
Web sites like justanswer.com/legal
...leave nothing to chance.
Traffic on JustAnswer rose 14 percent...and had nearly 400,000 page views in 30 days...inquiries related to stress, high blood pressure, drinking and heart pain jumped 33 percent.
Tory Johnson, GMA Workplace Contributor, discusses work-from-home jobs, such as JustAnswer in which verified Experts answer people’s questions.
I will tell you that...the things you have to go through to be an Expert are quite rigorous.
 
 
 

What Customers are Saying:

 
 
 
  • I can go as far as to say it could have resulted in saving my sons life and our entire family now knows what bipolar is and how to assist and understand my most wonderful son, brother and friend to all who loves him dearly. Thank you very much Corrie Moll Pretoria, South Africa
< Last | Next >
  • I can go as far as to say it could have resulted in saving my sons life and our entire family now knows what bipolar is and how to assist and understand my most wonderful son, brother and friend to all who loves him dearly. Thank you very much Corrie Moll Pretoria, South Africa
  • I thank-you so much! It really helped to have this information and confirmation. We will watch her carefully and get her in for the examination and US right away if things do not improve. God bless you as well! Claudia Albuquerque, NM
  • Outstanding response time less than 6 minutes. Answered the question professionally and with a great deal of compassion. Kevin Beaverton, OR
  • Suggested diagnosis was what I hoped and will take this info to my doctor's appointment next week.
    I feel better already! Thank you.
    Elanor Tracy, CA
  • Thank you to the Physician who answered my question today. The answer was far more informative than what I got from the Physicians I saw in person for my problem. Julie Lockesburg, AR
  • You have been more help than you know. I seriously don't know what my sisters situation would be today if you had not gone above and beyond just answering my questions. John and Stefanie Tucson, AZ
  • I have been dealing with an extremely serious health crisis for over three years, and one your physicians asked me more questions, gave me more answers and encouragement than a dozen different doctors who have been treating me!! Janet V Phoenix, AZ
 
 
 

Meet The Experts:

 
 
 
  • Dr. Keane

    Therapist

    Satisfied Customers:

    1262
    Clinical Psychology PhD, Licensed Professional Counselor with experience in marriage/family, teens and child psychology.
< Last | Next >
  • http://ww2.justanswer.com/uploads/DR/Dr.Keane/2013-8-20_204325_drkeane.64x64.jpg Dr. Keane's Avatar

    Dr. Keane

    Therapist

    Satisfied Customers:

    1262
    Clinical Psychology PhD, Licensed Professional Counselor with experience in marriage/family, teens and child psychology.
  • http://ww2.justanswer.com/uploads/RE/resolutions66/2011-1-17_05728_IMG8202smilingeditedforJustAnswer.64x64.jpg Elliott, LPCC, NCC's Avatar

    Elliott, LPCC, NCC

    Psychotherapist

    Satisfied Customers:

    5024
    35 years of experience as a Licensed Professional Clinical Counselor, National Certified Counselor and a college professor.
  • http://ww2.justanswer.com/uploads/formybunch/2010-12-06_191055_img_0975.jpg Kate McCoy, M.Ed, NBCC, LPC's Avatar

    Kate McCoy, M.Ed, NBCC, LPC

    Therapist

    Satisfied Customers:

    3733
    Over 20 years experience specializing in anxiety, depression, drug and alcohol, and relationship issues.
  • http://ww2.justanswer.com/uploads/DR/DrAkiraOlsen/2012-2-20_746_AkiraADpicmain.64x64.jpg Dr. Olsen's Avatar

    Dr. Olsen

    Psychologist

    Satisfied Customers:

    2336
    PsyD Psychologist
  • http://ww2.justanswer.com/uploads/norriem/2009-5-27_134249_nm.jpg Norman M.'s Avatar

    Norman M.

    Psychotherapist

    Satisfied Customers:

    2193
    UK trained in hypnotherapy, counselling and psychotherapy and have been in private practice. ADHP(NC), DEHP(NC), UKCP Registered and ECP.
  • http://ww2.justanswer.com/uploads/PsychologyProf/2010-07-15_171248_logos060400409.jpg Dr. Michael's Avatar

    Dr. Michael

    Psychologist

    Satisfied Customers:

    2177
    Licensed Ph.D. Clinical Health Psychology with 30 years of experience in private practive and as a clinical psychology university professor.
  • http://ww2.justanswer.com/uploads/KURTEMMERLING/2010-07-23_215531_just_ask_picture1.jpg Steven Olsen's Avatar

    Steven Olsen

    Therapist

    Satisfied Customers:

    1727
    More than twenty years of expertise in counseling, psychological diagnosis and education