Thanks for the reply .. Well, Depakote ( divalproax ) is quite commonly used for migraine headaches . So, you shall try it . The dose of 250 mg / day for the initial 4 days should be divided into 2 doses of 125 mg , each to be taken at morning and evening, meaning , that for first 4 days , you shall take half tablet of 250 mg depakote at morning after breakfast and and half tab of 250 depakote in evening after dinner , in this way you will be taking a total of 250 mg of depakote in a day , but it will be in divided doses .
Similarly , after the initial 4 days of continuing on 250 mg / day of depakote , you shall start on 500 mg / day of depakote , but this too is to be taken in 2 divided doses of 250 mg of depakote , one 250 mg of depakote taken in morning and the other 250 mg / day of depakote taken in evening .
The advantage of taking depakote in 2 divided doses is that it works throughout the day , and secondly , it has less possibility of producing side effects because of split in the total dose .
I suggest that you discuss this with your doctor and get started on the above mentioned way of takng depakote .
I hope this helps..
I wish you all the best..