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I already stopped the Zoloft because of the low libido, headaches and it wasn't enough to control my anger and irritability. I want to know which antidepressants are best at treating anger, irritability, body aches and fatigue and do not cause weight gain or low libido? The MDs I've seen don't know which meds are better at treating different types of symptoms. They just want to try them all sequentially until one works. That could take months of switching medications (and dealing with side effects). I'd like to know which med or class of meds work best at treating my particular symptoms.