Hi there ,
Welcome to Just answer !
Well, the fact that your mother has not been able to get relief from anxiety despite being on the drugs for quite a while is because , firstly after using a benzodiazepine like zanax ( alprazolam ) , one should not use buspar , because the prior use of zanax or any other benzodiazepine , reduces the anti anxiety effect of buspar , so that was the reason , why buspar did
not act the way it should have acted , and relieved your mother's anxiety , so it was a case of bad drug selection , if your doctor wanted to start your mother on an anti anxiety drug he should have started her on another benzodiazepine such as Klonopin or ativan or valium , etc.
Secondly your mother have been kept on a substandard dose of zanax , all this while , a dose of 0.25 mg , does not have the capacity to treat an anxiety disorder .
Thirdly , although zoloft ( sertraline ) is an ssri anti depressant , which is quite commonly used in anxiety disorder , but from what you have mentioned , it is quite clear that your mother is neither tolerating well nor responding well to the drug , so it is quite suggestive in itself , that your mother needs to be switched over to any other anti depressant.
So, above mntioned are the reasons as to why your mother's anxiety has not improved with the drugs that she has been taking.
Now, i shall mention below the treatment regime for your mother's anxiety , which you need to discuss with her doctor , who may scrutinize it if he pleases and then start on thsi regime , i am quite sure that this is going to help your mother in recovering from anxiety.
1) Switch over to another anti depressant from zoloft , because it has only shown side effects so far , and no positive effects . So anti depressants , to which your mother can switch over to are -- Paxil CR or Prozac or Effexor XR .aNY ONE OF THESE NEEDS TO be chosen by the doctor and its dose and time of intake is to be decided by him.
2) Stop zanax ( anyways 0.25 dose is so less to have any positive effect on anxiety) and Continue on Buspar , but see to it that you are having an adequate dose ( usually people are given 5 mg of buspar 2-3 times a day), the dose may be increased if no effect has been shown so far .
3) Start on Trazadone ( atypical anti depressant ) , which is also effective n treating anxiety as an assisting drug to the above mentioned ssri anti depressant .This trazodone needs to be given at night , before bedtime , and it also helps in getting a sound sleep , becuase of its sedative
So, i summarize the revised regime that your mother needs to be started on , after you have discussed this with her doctor-- A combination of 3 drugs-- 1 SSRI/ SNRI Anti depressant such as either paxil or prozac or effecxor , 1 anti anxiety drug and Trazodone .
I hope this helps..
I wish your mother rapid recoevry and i am quite positive that after starting on the above mentioned regime and continuing on it for 2-3 months your mother will feel very comfortable and recovered from anxiety , but she and you need to be patient for the first 2-3 weeks as this much time is required by these psychiatry drugs to reach their peak in the body.
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