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You are absolutely right. Alcohol, through a mechanism not fully understood, temporarily "washes out" neurotransmitters in the synapses (serotonin and norepinephrine), which results in lowered levels of these, which results in increased feelings of depression. Prozac effects only serotonin. That is why people who have drank heavily often feel depressed the next morning.
No problem with one glass of wine, but more than that is setting you up for increased feelings of depression.
Hope this helps.
I do tend to have a little depression, but mainly anxiety or a sense of being overwhelmed with the 4 little kids and the crazy eve hour 5-8p. may be prozac is not the best for me? or is there something else that may help my evening anxiety vs. alcohol?
Michelle, MPH, RD, LDN, MOM
Alcohol really doesn't mix well with any antidepressant or anti-anxiety med. It makes the antidepressant work less effectively, and it combines with the anti-anxiety meds to make you more sedated.
My suggestion to you would be Vistaril, 50 mg..... a mild anti-anxiety drug that is not addicting.