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Well, when Adderall ( amphetamines) and Tricyclic anti depressants ( TCAs ) like Imipramine are used together , then both these drugs increase each others activity and potentiate actions of the other drug.First , Adderall increases the activity of TCAs like imipramine ,and this imipramine with increased activity will increase the concentration of dextro amphetamines in the brain and heart , thereby potentating the effects of adderall ( amphetamines ) in the heart , and thus causing cardiac side effects such as Increased heart rate ( tachycardia ) , increased blood pressure ( hypertension) , palpitation
, Myocardial infarction ( cardiac arrest ) , sudden death.
Since we have beter alternative anti depressants than imipramine and other TCAs , in the form of SSRI anti depressants such as Paxil ( paroxetine ) , Zoloft ( sertraline) , Prozac (fluoxetine ) , which do not cause any harmful interactions with ADDERALL, UNLIKE IMIPRAMINE, THEN WHY TO TAKE RISK.
So, i suggest you switch over to one of the mentioned above SSRI anti depressants , and get started on it , and avoid any untoward side effects which are produced by the combination of adderall and imipramine.
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I wish you best of health.
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