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It is not too much to take by accident. it typically does not provide any additional benefit for most patients. However, there are patients that make far too much stomach acid because of an underlying endocrine problem, and in these people, the omeprazole can be prescribed in doses up to 360 mf per day, in 3-4 divided doses.
The omeprazole is generally well tolerated at the higher dose. There is a slightly higher risk of minor side effects, such as headache, nausea, or diarrhea, but there is not any major issue with accidentally taking a dose of 80 mg at one time.
There also is no problem with interactions with the zonisamide caused by a higher dose of the omeprazole.
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