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Edema usually bilateral (happens on both sides).
Swelling that happens on one side can be due to a clot in the veins in the leg but that would usually cause swelling not limited to the ankle. It will lead to swelling extending up into the leg as well.
Other causes include bursitis or swelling of the bursa.
An ultrasound of the ankle and leg would likely be able to tell exactly what it is.
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