Hello, my dad lives in Korea. He is doing kidney dialysis 3 times a week for 4 hours per dialysis at a hospital. It's been 6 years. He recently got pneumonia
and treated (2-3 weeks ago), but he is now diagnosed with TB (5 days ago). And he has depression, insomnia, and hypertension for a couple of years. He is very sensitive to all kinds of drugs and particularly allergic to some kinds of drugs with pyrine (antipyrine(phenazone), aminopyrine(amidopyrine), sulpyrine(dipyrone)) and glucose.
He has been taking medicines: Zolpidem
, Klonopin, Paroxetine, antihypertensive, and anti-TBs (Isoniazid
100 mg, Rifampicin 450 mg, Ethambutol HCl 400 mg, Pyrazinamide 500 mg, and Vitamin B Pyridoxine HCl 50 mg). He has started anti-TBs 5 days ago and since then his blood pressure
is around 200-220 (lower blood pressure is about 95). He has been hospitalized since yesterday due to hypertension, but doctors prescribed a lot more antihypertensives (yesterday) and it is now 195. Doctors prescribed Minoxidil (antihypertensive) more today.
My family considers this hypertension as side effects from drug interactions, because this started exactly 24 hours after he began taking the anti-TBs. He has hypertension thus has been taking medicine, but it is tamed usually well with the antihypertensive he has been taking. For three days, his blood pressure is above 200. I am really concerned because doctors seem to not taking our thoughts seriously. Doctors keep saying that nothing is wrong with the medicines prescribed…and they just keep increasing doses of Zolpidem.
I found there are some studies on side effects of anti-TBs with Benzo kind drugs. And, SSRIs and anti-TBs share common inhibitory effects on monoamine oxidase. So, I have been wondering if any of the drugs he is taking now could have caused this too-high blood pressure. Any advice will be valuable.