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Dr. David
Dr. David, Board Certified Physician
Category: Medical
Satisfied Customers: 43482
Experience:  Experienced Physician trained in New York City. I'm ready to help.
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My wife has suffered from chronic severe pruritis over the

Customer Question

My wife has suffered from chronic severe pruritis over the past twenty-five years. She's been to a multitude of doctors, allergists, dermatologists, etc., including the Cleveland Clinic, all to no avail.
We're hopeful that recent breakthroughs relating to the GRP peptide, that carries itch signals to the GRPR peptide receptor, will lead to an answer. However, my question is more directed toward whether Candida can play a role in her symptoms?
Submitted: 7 months ago.
Category: Medical
Expert:  Dr. David replied 7 months ago.

This is Dr. David

http://www.nature.com/nature/journal/v448/n7154/full/nature06029.html

is a good article about GRP peptide mediates itch sensation in the spinal cord.

https://source.wustl.edu/2013/10/scientists-unravel-mechanisms-in-chronic-itching/

http://phenomena.nationalgeographic.com/2013/05/23/first-stop-on-the-itch-express/

none of these articles mention candida or yeast.

most likely yeast is not playing a part in this chronic severe itching

has she tried neurontin (gabapentin) or lycia (pregabalin) nerve pain medications to help her itching symptoms?