How JustAnswer Works:
  • Ask an Expert
    Experts are full of valuable knowledge and are ready to help with any question. Credentials confirmed by a Fortune 500 verification firm.
  • Get a Professional Answer
    Via email, text message, or notification as you wait on our site.
    Ask follow up questions if you need to.
  • 100% Satisfaction Guarantee
    Rate the answer you receive.
Ask Anthony Bray, MD Your Own Question
Anthony Bray, MD
Anthony Bray, MD, Doctor
Category: Medical
Satisfied Customers: 10337
Experience:  14 years experience in the field of Family Practice
13781349
Type Your Medical Question Here...
Anthony Bray, MD is online now
A new question is answered every 9 seconds

Bray- can ibuprofen can ulcers? why is that ?how does it do

Customer Question

for Anthony Bray- can ibuprofen can ulcers? why is that ?how does it do that? and can the ulcer become a gi bleed? ould the ibuprofen cause it?
Submitted: 6 months ago.
Category: Medical
Expert:  Anthony Bray, MD replied 6 months ago.
Hello!Yes IBUPROFEN may cause ulcers of the stomach..The stomach is in part protected by some substances known as prostaglandins ....Some prostaglandins are related also to the body response to inflammation / some promote inflammatory response IBUPROFEN INHIBITS prostaglandins So this may strip some of stomach protection...Stomach acid without the protein give presence of prostaglands is more likely to be injured by the stomachs acid >> gastritis to gastric ulcers ...IBUPROFEN ALSO may promote bleeding if you have an ulcer Ibuprofen reacts to inhibit platelets which help STOP bleeding ...Similar to ASPIRIN but aspirin has a longer reaction to inhibit platelet function ...IBUPROFEN INHIBITS plates for about 8 hours after dose ... So IBUPROFEN both may increase risk of ulcers and may promote more readily bleeding of any injury ...I hope that this information is helpful for youLet me know if you have further questions or concernsI will be happy to get back with youBest regards!Anthony Bray MD
Customer: replied 6 months ago.
ok with an GI bleed what are the vital signs that you will see? why will the respiratory rate be elevated?
Expert:  Anthony Bray, MD replied 6 months ago.
Hello again,With a GI bleed you would expect that the blood volume decreases...blood pressure drops..pulse( heart rate increases ) as compensation...( less blood must travel faster to compensate and keep up with oxygen delivery ) similarly increase in respiratory rate needed...blood flowing more rapidly ( less total blood though ) So BREATH is faster in rate to bring in oxygen more quickly to oxygenate the blood...These are compensations for the blood loss ....
Expert:  Anthony Bray, MD replied 6 months ago.
I hope that this helps and makes sense !Best regards !!Anthony Bray MD
Customer: replied 6 months ago.
how about the pulses in GI bleed? would they be bounding?
Customer: replied 6 months ago.
what are your assessents normally in GI bleed?
Expert:  Anthony Bray, MD replied 6 months ago.
Hello again,Not necessarily ...if you had 5 or 10 percent blood loss then you could have bounding pulses as faster heart rate and increased contraction force of heart beat BUT too much blood loss may lead to hypovolemic shock == thread weak pulses ..if you had 25 to 50 percent blood loss then the latter may be the case .....
Expert:  Anthony Bray, MD replied 6 months ago.
Hello again...You check and watch vitals ...Telemetry monotring ..Serial blood samples ...depends on scenario...Brisk bleed you want two large bore IVs...perhaps start saline if you need due to volume depletion ... Transfusion if situation calls for it
Expert:  Anthony Bray, MD replied 6 months ago.
Watch for hypotension (NP less than 100/60..)Tachycadia -- resting pulse over 100...Hemoglobin less than 7.0 usually indicates need for transfusion but active bleeding and unstable vitals you would not WAIT for hemoglobin to drop....
Expert:  Anthony Bray, MD replied 6 months ago.
Rapid bleeding as blood per rectum you would treat as life threatening similar to gun shot wound....
Customer: replied 6 months ago.
what are the blood tests ordered in GI beed?
Expert:  Anthony Bray, MD replied 6 months ago.
CBC / metabolic profile mainly ...Other tests might be considered depending on suspect source ...Inflammatory markets might be included if you suspected ulcerative colitis or Crohn's...The meatabolic profile includes renal function (BUN usually abnormally elevated in GI bleed ) If ulcer suspect an H. PYLORI test may be ordered....Type and cross match for 2 to 4 UNITS of blood ....
Expert:  Anthony Bray, MD replied 6 months ago.
Chronic liver disease may be associated with esophageal varies ...
Expert:  Anthony Bray, MD replied 6 months ago.
Check for blood coagulation factors >> aPTT, PROTIME ...

Related Medical Questions