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Blood clot in the leg veins is more likely possibility also called deep vein thrombosis.
Doppler ultrasound should be considered to check for blood clots in the leg veins.
Medication side effect can cause electrolyte abnormalities and cramps.
Peripheral nerve disease from thyroid and diabetes can cause such symptoms as well.
Stroke in the brain is also possible.
That can be checked by the brain scan.
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DVT of the leg vein commonly present in great saphenous vein or common iliac vein.
Hand swelling is due to the DVT in a different vein upper extremity vein.
Another possibility is peripheral arterial disease of the leg and arm.
The arteries can be clogged given your strong history of heart disease, and diabetes.
That can be checked by the angiogram of the legs and arms.
Can be fixed by angioplasty.
Medication related side effect is unlikely but still possible especially with coversyl.
MRI scan of the brain and angiogram of the brain blood vessels will show any stroke or any significant blockage of the blood vessels suggesting future stroke possibility.