Have Medical Questions? Ask a Doctor Online!
Hi there ...
Thank you for your question ...
Please tell me have you had test to rule out the possibility of associated other autoimmune disease with Graves disease which could be the cause of ulcers like scleroderma ?
Ok thats fine , if everything is normal than it is highly likely that antibodies like thyroid stimulating antibodies have negative effect against skin and skin vessels leading to cutaneous vasculitis associated with ulcer formation .
Suppression of immune system with steroids can be helpful to reduce the frequency and occurrence of ulcers .
I will suggest you to ask your Endocrinologist to have immunosuppresive therapy along with anti-thyroid drugs to see response , if ulcers heal than this is indication that underlying immune hyper function is the reason of skin ulcers .
Because in hyperthyroidism hyperfunctioning of vasomotor center is also associated with skin issues.
Positive feedback will be appreciated .
Yes there are other immune modulators but they are not directly indicated once if steroids are not beneficial than those agents are indicated .
So I wish you should start steroids .
Good luck .
Even if biopsy are not suggestive of inflammation or vasculitis but still once you should have trial of steroids .