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Dr. David
Dr. David, Board Certified Physician
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My first Ana positive 1:80 speckled this Ana negative but gh

Customer Question

My first Ana positive 1:80 speckled this Ana negative but high sensitivity anti rnp was positive...I believe I have ehlers danlos. I thought if Ana negative rnp would be negative too
Submitted: 1 year ago.
Category: Medical
Customer: replied 1 year ago.
I have hypermobile joints pain depression fatigue and vision issues MRI showed some arthritis but ruled out ms...I have little appetite and lost sixty pounds I experience terrible headaches and get increased heart rate when in shower
Customer: replied 1 year ago.
Both my son and I meet all of the criteria on the Brighton scale and has soft velvety skin and scar weird
Expert:  Dr. David replied 1 year ago.

This is Dr. David

there is genetic testing which can confirm if you have ehlers danlos syndrome.

it is a rare condition and some rheumatologist may not have experience with it.

you might have to go to a larger city university medical center rheumatology program to see a doctor with experience with it.

are you close to a large city university medical center?

Customer: replied 1 year ago.
I'm in Vancouver Canada my neurologist is reffering me to geneticist and pain did I get a positive anti rnp and a negative Ana?
Customer: replied 1 year ago.
Eds is genetic not auto immune so could it mean I have eds plus mctd...
Expert:  Dr. David replied 1 year ago.

these are different autoimmune testing.

autoimmune testing can be unpredictable and some patients who have conditions like lupus can take years to diagnose because of the nature of the disease and testing.

you need more testing with a specialist with

antibodies to double-stranded DNA (anti-dsDNA) tests,
antibodies to histone tests,
antibodies to phospholipids,
antibodies to Ro/SS-A and La/SS-B,
antibodies to Sm target Sm proteins in the cell nucleus,

and other tests to see if you have an autoimmune disorder or not.

Customer: replied 1 year ago.
I did that had positive on screen negative on all but ant rnp @ 1.38
Expert:  Dr. David replied 1 year ago.

could be a false positive there.

you may not have autoimmune disorder

you might need those tests repeated in 6-12 months again.

and genetic testing to check for EDS

Customer: replied 1 year ago.
Thank you
Customer: replied 1 year ago.
Expert:  Dr. David replied 1 year ago.

please leave positive rating above the chat box so I can get credit for helping you today

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you can always reach me with "a question for Dr. David" in the medicine or oncology categories if you have any other questions

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Expert:  Dr. David replied 1 year ago.

do you have any other questions?

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