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It could be allergic dermatitis. You should take over-the-counter oral antihistamine such as Zyrtec and topical 1% hydrocortisone cream (two or three times a day). But you should not use opical 1% hydrocortisone cream for more than two weeks because of possible side effects, such as thinning of the skin.
Okay. It is not allergic dermatitis. Any skin change? How old are you? How tall are you? How much do you weigh? Any medical problems? Any surgeries? Any other medications? Do people around you have similar problem? Any family medical history?
No skin change?
Enterobius vermicularis (pinworm) is possible because of nocturnal anal pruritus although it is more common in children as compared with adults. Erythrasma, an infection withCorynebacterium minutissimum, is more common in older adults. But it presents as a slowly enlarging area of pink or brown dry skin.
Enterobius vermicularis (pinworm) can be diagnosed via a pinworm paddle test. This is a clear plastic paddle coated with an adhesive surface on one side that is pressed against several areas of the perianal region. The paddle is then placed onto a glass slide and eggs can be visualized under a microscope. The diagnostic yield is greatest if the test is performed at night or first thing in the morning, prior to bathing. The diagnosis of erythrasma is based upon physical appearance and the presence of coral-red fluorescence with a Wood's lamp.
You should see a dermatologist to have the tests. S/he may do a skin biopsy if necessary.