It does not matter from what cause, but a urinary blockage can result in kidney damage.
I am a double board certified clinical doctor. We never say wait on a urinary blockage as damage can be irreversible.
I have checked the major pharmaceutical data bases including clinical pharmacology, as well as FDA prescribing information and find no evidence that pantoprazole would augment the effect of vesicare to the point of urinary obstruction. Even if this were the case, examination should not be delayed.
In addition, acute renal damage would not necessarily have swelling in the legs, at least not right away, and the point would be to prevent that symptom.
Not even all chronic renal damage shows this symptom for some time.
In fact, the sudden cessation of urination can happen for multiple reasons, and might not be related to your medications at all. We can not examine you or do testing. But, this is exactly what you need at this point.
DO NOT DELAY THIS ASSESSMENT.
This is not a normal situation. I believe you need immediate assessment, today.
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