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Do you mean Doxycycline(Tabocine)? Which type of arthritis? Give more details and the history.
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Basically this medication is moderately effective in the treatment of early rheumatoid arthritis and is used less frequently as a disease-modifying anti-rheumatic drugs (DMARDs). Regarding its usage as a disease modifying osteoarthritis drug, it is not used frequently, however some trials and studies have shown that doxycycline may slow the radiographic progression in some patients.