Have Medical Questions? Ask a Doctor Online!
This is Dr. David
yes, there can be interactions between Spasmex (or trospium) and tricyclics.
the combination can increase risks for hyperpyrexia and can increase anticholinergic adverse effects.
you made the right decision.
take the antidepressant
and talk to your doctor at your next appointment about this possible interaction.
let me know if you have other questions.