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Well for starters she should get tested ....there are treatments for herpes ( suppression) and for hepatitis B or C . There is usually definitive treatment for tuberculosis.( If exposure but not active pulmonary disease then preliminary testing is needed ...if not exposed to extent to mount immune response then she may not need treatment for TB)
The above would be the indicated start point medically. It sounds that the relationship would have its own issues ....
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Anthony Bray MD