That is very unfortunate.
This is due to the continuous immune system overdrive related action.
Your husband has developed this rash persistently.
Instead of oral prednisone strong topical steroid cream like clobetasol can be used --will have less side effects.
Also immunomodulating creams like tacroliums can be tried instead of prednisone.
Usually this type of reaction may last for several weeks.
But this will gradually subside over time.
A dermatologist also should be consulted with.
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