Thank you for the additional information.
It is true that there is no need to treat clear mucus from the sinuses. The mucus can become infected and would require treatment. But if there is no infection, the issue of treatment is based solely on how bothersome the mucus is.
You are already taking the usual primary treatment for the mucus - steroids, such as prednisone and medrol. However, when there is inflammation from lupus that does not respond well to a steroid, the next consideration would be whether to use a medicine that suppresses the immune system, such as cyclophosphamide or azathioprine
. Since the stronger medicines also carry more potential for side effects, many doctors would prefer to avoid using these medicines for sinus mucus. It is more common that these medicines may be needed if the lupus is affecting the lungs
, but not as common for the sinuses. However, if the problem is of such severity that something must be done, one of these medicines would be the next consideration.
If you need any clarification, please let me know.