How JustAnswer Works:
  • Ask an Expert
    Experts are full of valuable knowledge and are ready to help with any question. Credentials confirmed by a Fortune 500 verification firm.
  • Get a Professional Answer
    Via email, text message, or notification as you wait on our site.
    Ask follow up questions if you need to.
  • 100% Satisfaction Guarantee
    Rate the answer you receive.
Ask Dr. Vikas Your Own Question
Dr. Vikas
Dr. Vikas, Doctor
Category: Medical
Satisfied Customers: 2230
Experience:  MBBS; MD
Type Your Medical Question Here...
Dr. Vikas is online now
A new question is answered every 9 seconds

If I have been on diazepam 10 mg 4 times daily for years, and

This answer was rated:

If I have been on diazepam 10 mg 4 times daily for years, and wean myself down daily to none in 2 weeks, then for how long will I still test positive for benzodiazapines?

Dr. Vikas :


Dr. Vikas :

Any medicine may persist in the body for 4-5 times its elimination half life after the last dose taken. The elimination half life of Diazepam is 20-50 hours.


So after the last dose I am looking at 250 hours after the last dose?

Dr. Vikas :

although a lot also depends on other factors like body weight, duration of use, physical condition but in most cases the drug is completely flushed out from the body within 10-14 days if we consider its elimination half life of 20-40 hours.

Dr. Vikas :



OK, thank you.

Dr. Vikas and 4 other Medical Specialists are ready to help you

I have not finished yet. Please note that "Urine concentrations of metabolites are detectable for several days to weeks after last use. Urinary excretion of unchanged drug is less than 1%.

source - Drugs and Human Performance FACT SHEETS - Diazepam
Please also see this link below.

In chronic users, it may take few weeks (1-6 weeks or more)and till then the medicine can be detected in urine.

Please see the link below for more information.

The main reason behind this is because " The initial distribution phase is followed by a prolonged terminal elimination phase (half-life up to 48 hours). The terminal elimination half-life of the active metabolite N-desmethyldiazepam is up to 100 hours. Diazepam and its metabolites are excreted mainly in the urine, predominantly as their glucuronide conjugates."

source -

I hope this helps, please feel free to discuss further if you have any doubt or other question in your mind.

Kind regards


Related Medical Questions