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Weakness doesn't seem to be an issue - it's the pain that is limiting her mobility. Tenderness also does not seem to be present. When I have massaged the affected area for her, a definite "sweet spot" regarding pain has been just inside her right shoulder blade (perhaps a bit higher towards her neck as well). Advil: 200 mg. Aleve: 220 mg (per bottle info). I do not believe she has ever exceeded the 24 hr dosage recommendations on the packaging. For example, when she has reached for the Aleve, she would take two tablets, but then no more for a few days. Definitely utilized for temporary relief and not as a regimen.