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Yes, this has been reported. The two medicines,while similar, have different chemical structures. This difference can have very different effects on the immune system of some patients.
Procrit is made using recombinant DNA technology and is identical to human erythropoietin and, as as such is highly hypo-allergenic.
Here is a very good article that investigated just this issue:
Curr Med Res Opin. 2003;19(5):430-2. Epoetins: differences and their relevance to immunogenicity. Haselbeck A.
Does this make sense to you?
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I need a copy of the Curr Med Res Opin. indicated in your reply.
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