How JustAnswer Works:

  • Ask an Expert
    Experts are full of valuable knowledge and are ready to help with any question. Credentials confirmed by a Fortune 500 verification firm.
  • Get a Professional Answer
    Via email, text message, or notification as you wait on our site.
    Ask follow up questions if you need to.
  • 100% Satisfaction Guarantee
    Rate the answer you receive.

Ask Dr. Gupta Your Own Question

Dr. Gupta
Dr. Gupta, Doctor
Category: Medical
Satisfied Customers: 7834
Experience:  Vastly experienced MD Physician with 19 years of experience.
Type Your Medical Question Here...
Dr. Gupta is online now
A new question is answered every 9 seconds

Having a tough time since having a bad reaction to 2 doses

Resolved Question:

Having a tough time since having a bad reaction to 2 doses of Zyvox a week ago. It seems like my symptoms are in line with peripheral nueropathy. I'm scared I have done irreversible damage. Can a Dr. help me think this through?
Submitted: 2 years ago.
Category: Medical
Expert:  Dr. Gupta replied 2 years ago.

MD Doc :

Hello & welcome to Just Answer!

If you have any questions after reading my answer, be sure to let me know.

MD Doc :

Sure,

MD Doc :

If you are really worried about Peripheral neuropathy, I would recommend that you look at the possible symptoms and get a clinical examination

MD Doc :

This is very unlikely as a bad reaction to 2 doses of Zyvox,

MD Doc :

but a clinical examination and if required a neuro evaluation for weakness / paresthesia and finally a nerve conduction test would help confirm that this is indeed not the cause of your possible symptoms

MD Doc :

Just as a matter of scientific evidence, almost all cases of Linezolid associated Peripheral neuropathy have occurred in patients who have taken it longer than 28 days

MD Doc :

Please remember to accept the answer by pressing the GREEN accept button, do get back for any clarifications

Customer: I would like to discuss further with you but it appears you are off line
MD Doc :

I am online

MD Doc :

please let me know as to what you are interested in asking

MD Doc :

in case we are able to chat, great,

MD Doc :

if we are not, let me know your questions so that we can continue our interaction

Customer: Thank you for your quick response. It has been one hell of a week for me. 7 days ago I woke up after my second dose of 600 mg Zyvox extremely irritable and light sensitive to the eyes. I immediately stopped taking the Zyvox. The next morning however I woke up and all my leg muscles were severely cramped, painful and I felt like I was losing my balance forward. Now that has progressed to burning in my feet and lower legs and general loss of sensation throughout my body. I still feel but it just feels kind of dull. When I stand up I feel a little off balance and slight motion sicness. My muscles twitch and ache throughout my body. Overall I just feel off. Also my lymph nodes in my neck have been swollen. It seems like my symptoms are peripheral nueropathy and I'm really scared. I'm only 41. Is there a possible alternate diagnosis? If the Zyvox did effect my nerves is it permant or irreversible or did I just aggravate the nerves inflame them etc.. Can you help me think this through?
Dr. Gupta, Doctor
Category: Medical
Satisfied Customers: 7834
Experience: Vastly experienced MD Physician with 19 years of experience.
Dr. Gupta and 6 other Medical Specialists are ready to help you
Expert:  Vakul Aren replied 2 years ago.
Spontaneous causation of serotonin Syndrome are reported with the use of the drug Linezolid/Zyvox along with serotonergic drugs which include antidepressants and mepiridine.Symptoms would include tremors,agitation and restlessness,diarrhea,palpitations,muscle spasms,dilated pupils,sweating,ataxia and mental confusion.If you have inardevently taken the Zyvox with a SSRI antidepressant,such a situation may arise.The side effects of Zyvox alone are unlikely cause such a problem though optic and peripheral neuropathy both have been reported with the drug after prolonged use.You need to contact your doctor/PCP who can examine you and determine the future course of events.it would be prudent to discontinue the drug till such time.You may need specific treatment urgently if Serotonin Syndrome is suspected.
Expert:  Dr. Gupta replied 2 years ago.
I would have to say that from your description it would appear that peripheral neuropathy is a possibility.
However, this is extremely uncommon with 2 doses of Linezolid only. This suggests that this may be a temporary problem that may be reversible with the passage of time,
However you MUST get an urgent medical consultation for the same to confirm the diagnosis with specific tests, and then take appropriate treatment as needed,
Warm regards
Customer: replied 2 years ago.
Dr I am still having a very hard time. I still have symptoms from a week ago. When I read the pereferal nueropathy symptoms it is exactly what I have. How do I know if I have permanent nerve damage or just injured or inflamed the nerves but they will recover in time. I can't believe 2 pills would do this to me. Basically 1200 mg of Zyvox total over a 24 hour period can debilitate me for life. My symptoms wax and wane throughout the day. They get worse then ease up. How long will these symptoms last? Thank you in advance for you kind and competent response.

JustAnswer in the News:

 
 
 
Ask-a-doc Web sites: If you've got a quick question, you can try to get an answer from sites that say they have various specialists on hand to give quick answers... Justanswer.com.
JustAnswer.com...has seen a spike since October in legal questions from readers about layoffs, unemployment and severance.
Web sites like justanswer.com/legal
...leave nothing to chance.
Traffic on JustAnswer rose 14 percent...and had nearly 400,000 page views in 30 days...inquiries related to stress, high blood pressure, drinking and heart pain jumped 33 percent.
Tory Johnson, GMA Workplace Contributor, discusses work-from-home jobs, such as JustAnswer in which verified Experts answer people’s questions.
I will tell you that...the things you have to go through to be an Expert are quite rigorous.
 
 
 

What Customers are Saying:

 
 
 
  • I feel so much better today, and upon further investigation believe that there is a chance that the responses I got saved me from a serious, even life threatening situation. I am very grateful to the experts who answered me. Susan O. USA
< Last | Next >
  • I feel so much better today, and upon further investigation believe that there is a chance that the responses I got saved me from a serious, even life threatening situation. I am very grateful to the experts who answered me. Susan O. USA
  • I can go as far as to say it could have resulted in saving my sons life and our entire family now knows what bipolar is and how to assist and understand my most wonderful son, brother and friend to all who loves him dearly. Thank you very much Corrie Moll Pretoria, South Africa
  • I thank-you so much! It really helped to have this information and confirmation. We will watch her carefully and get her in for the examination and US right away if things do not improve. God bless you as well! Claudia Albuquerque, NM
  • Outstanding response time less than 6 minutes. Answered the question professionally and with a great deal of compassion. Kevin Beaverton, OR
  • Suggested diagnosis was what I hoped and will take this info to my doctor's appointment next week.
    I feel better already! Thank you.
    Elanor Tracy, CA
  • Thank you to the Physician who answered my question today. The answer was far more informative than what I got from the Physicians I saw in person for my problem. Julie Lockesburg, AR
  • You have been more help than you know. I seriously don't know what my sisters situation would be today if you had not gone above and beyond just answering my questions. John and Stefanie Tucson, AZ
 
 
 

Meet The Experts:

 
 
 
  • Dr. Thomas, MD

    Board Certified Physician

    Satisfied Customers:

    46349
    Internal Medicine--practice all of internal medicine, all ages, family, also Integrative, CAM, etc
< Last | Next >
  • http://ww2.justanswer.com/uploads/DR/DrThomasMd/2012-7-25_134438_Imagess1.64x64.jpg Dr. Thomas, MD's Avatar

    Dr. Thomas, MD

    Board Certified Physician

    Satisfied Customers:

    46349
    Internal Medicine--practice all of internal medicine, all ages, family, also Integrative, CAM, etc
  • http://ww2.justanswer.com/uploads/MY/mysticdoc/2012-6-8_15615_mysticdoc3.64x64.jpg Dr. D.J.'s Avatar

    Dr. D.J.

    Board Certified Physician

    Satisfied Customers:

    14679
    MD
  • http://ww2.justanswer.com/uploads/agketch/2008-7-14_184046_drketchresized.jpg Dr. Ketch's Avatar

    Dr. Ketch

    Board Certified Physician

    Satisfied Customers:

    76
    Medical Degree, Former Assistant Professor at School of Medicine at Yale University
  • http://ww2.justanswer.com/uploads/FA/FamilyPhysician/2013-8-31_191624_JA550x500Photo.64x64.jpg Family Physician's Avatar

    Family Physician

    Doctor

    Satisfied Customers:

    2562
    Emergency Medicine and Family Practice for over 26 years
  • http://ww2.justanswer.com/uploads/DR/drappapo/2013-8-16_22576_drdavid.64x64.jpg Dr. David's Avatar

    Dr. David

    Board Certified Physician

    Satisfied Customers:

    224
    Treat children/young adults, former chief resident, multiple publications
  • http://ww2.justanswer.com/uploads/DrDLove/2009-08-12_141522_DrDLove.jpg Dr. D. Love's Avatar

    Dr. D. Love

    Doctor

    Satisfied Customers:

    11961
    Family Physician for 10 years; Hospital Medical Director for 10 years.
  • http://ww2.justanswer.com/uploads/CO/commissure/2011-4-15_192514_REISD20080926JR1090.64x64.jpg Dr. David's Avatar

    Dr. David

    Board Certified Physician

    Satisfied Customers:

    10667
    Experienced Physician trained in New York City. I'm ready to help.