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Dr. Robert
Dr. Robert, Doctor
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What do high thyroid peroxidase antibodies indicate

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What do high thyroid peroxidase antibodies indicate?
Hello,
Welcome to justanswer and thank you for your question.

Well, Thyroid peroxidase (TPO) is an enzyme which is found in thyroid follicle cells where it converts the thyroid hormone T4 to T3.
Also, Moderate thyroid peroxidase levels may indicate that a patient has thyroid cancer, anemia, rheumatoid arthritis or Type 1 diabetes.

According to Mayo clinic- The presence of thyroid peroxidase antibodies in your blood suggests that the cause of thyroid disease is due to an autoimmune disorder such as Hashimoto's disease or Graves' disease.

Having High concentrations of thyroid peroxidase antibodies suggest the presence of Hashimoto's or Graves' Disease.

Link- http://www.labtestsonline.org/understanding/analytes/thyroid_antibodies/test.html




Customer: replied 5 years ago.
If TPO is increased will the other thyroid tests also show something?
Yes, usually Physicians will usually order a TPO when other test results measuring the levels of T3 or T4 hormone or TSH (thyroid stimulating hormone) show irregularities.

Also ,thyroid peroxidase antibody test is done in order to determine the specific cause
Yes, T3, T4 , TSH will show irregularity when TPO is increased.



Customer: replied 5 years ago.
Are T3, T4 and TSH the three tests that are always done?
Yes, these 3 tests are necessary for the diagnosis, of Thyroid disorder.

Check this link-
http://thyroid.about.com/od/gettestedanddiagnosed/a/bloodtests.htm
Customer: replied 5 years ago.
When one goes for regular blood tests are all three done?
Well, there are several common blood test panels that your doctor may recommend. In case if someone does not have any specific symptoms, then doctor do not advise for Thyroid tests.

Complete blood count called as CBC measures the amounts of red blood cells, white blood cells, platelets and iron in your blood.

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Customer: replied 5 years ago.
Do raised TPO mean hypothyroidism or hyperthyroidism or both?
Well, A high level of thyroid peroxidase means that a patient has Graves' disease or Hashimoto's disease.
And, In patients who have hypothyroidism, high TPO is indicative of Hashimoto's disease. In hyperthyroid patients, high TPO is indicative of Graves' disease.

This test - TPO will not tell if patient has Hypothyroidism or Hyperthyroidism.

In most cases, Thyroid-stimulating hormone (TSH): this is the single most useful lab test in diagnosing thyroid disease.
In case of hyperthyroidism, TSH level is Low, whereas in case of hypothyroidism, the TSH levels is high.

Customer: replied 5 years ago.
Are both conditions easily treatable?
Yes, with appropriate management both of these conditions can be treated.
You need to consult a Endocrinologist for the management of this issue.
Such symptoms, can be treated with medications.

Good luck and take care



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