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There are many possible causes of an elevated CEA level, but it has not been associated with an E. coli infection. It has been reported to be increased in smokers, as well as with inflammatory conditions, ulcerative colitis, Crohn's disease, pancreatitis, cirrhosis, peptic ulcers, COPD, and benign breast disease. It is because of the high incidence of other conditions that can cause an elevated CEA that it is generally not considered an effective screening process. In a person with a history of a known malignancy that develops an elevated CEA, there should be an investigation for recurrence of the cancer, even if there is a condition present that can cause an elevated level.
I have also done Ca 125 which was negative and a fecal stick also negative. Would you than feel this test result supports having a Colonoscopy?
Most doctors do not use CEA as a screening test, because of the number of conditions that cause an elevated result, as noted above. If it is chosen to use it as a screening test, then the next step would be to perform a colonoscopy. There is also a recommendation that all persons receive regular colon cancer screening, and a colonoscopy every ten years is one of the recommended regimens. Therefore, it would be reasonable to perform a colonoscopy, but most doctors would recommend the screening colonoscopy and would not have performed the CEA.