How JustAnswer Works:

  • Ask an Expert
    Experts are full of valuable knowledge and are ready to help with any question. Credentials confirmed by a Fortune 500 verification firm.
  • Get a Professional Answer
    Via email, text message, or notification as you wait on our site.
    Ask follow up questions if you need to.
  • 100% Satisfaction Guarantee
    Rate the answer you receive.

Ask Dr. Owen Your Own Question

Dr. Owen
Dr. Owen, Board Certified Physician
Category: Medical
Satisfied Customers: 55753
Experience:  Board Certified in 2 Specialities & US Medical Graduate
18703594
Type Your Medical Question Here...
Dr. Owen is online now
A new question is answered every 9 seconds

In my sisters autopsy 736 ng/mL of alprazolam was found. I

Resolved Question:

In my sisters autopsy 736 ng/mL of alprazolam was found. I would like to know how many 2MG tablets she would have had to have taken?
Submitted: 4 years ago.
Category: Medical
Expert:  Dr. Owen replied 4 years ago.
Hello,
This depends when she took them and when she died?
And, it is hard to convert a mass in mg to a density (mg/dL) - and you would have to know her weight and height and total volume of blood in her body too.
Customer: replied 4 years ago.
I have the answers to all these questions.
Expert:  Dr. Owen replied 4 years ago.
If you have information - please fill me in - thank you.
Customer: replied 4 years ago.

VI. Obesity (BMI = 31.0)

Height 67 in.

Weight 90 kg.

It does not show in the autopsy the total volume of blood in her body.

 

The autopsy states "accident". She took the pills aprox. 2-3 hours prior to death.

Expert:  Dr. Owen replied 4 years ago.
Hello,
So is this considered an overdose?
Customer: replied 4 years ago.

Yes, they say accidental overdose. That's why I want to know how many pills were taken?

 

 

I. Heart (460 g)

A. No significant atherosclerosis of coronary arteries

II. Pulmonary congestion and edema (combined weight 1430 g)

III. Liver with fatty metamorphosis

IV. Urinary bladder with approximately 200 cc of retained urine

V. Cholecystectomy, remote

VI. Obesity (BMI = 31.0)

VII. No fatal trauma identified

COMMENT: Toxicological analysis of femoral blood revealed an alprazolam level of 736 ng/mL.

Expert:  Dr. Owen replied 4 years ago.
Hello,
I will assume she had the average blood volume of 5 liters - 5000 ml - so this means she had 736ng/mL x 5000mL = 3,680,000ng of medication.
1 gram = 1,000,000,000 ng
1 gram = 1,000mg
Therefore 3,680,000ng x 1000mg/1,000,000,000 = 3.68 mg in her blood stream - and this is a lot - so even though the tablets were 2mg - given that it had to get into her blood stream too - she probably had a few hours - so most likely she had about 30 to 50 tablets in her body - so about 60 to 100mg of medication to equal just the 3.68mg in her blood. Quite an overdose - this was no accident - sorry.
I hope this helps,
Dr. Owen, Board Certified Physician
Category: Medical
Satisfied Customers: 55753
Experience: Board Certified in 2 Specialities & US Medical Graduate
Dr. Owen and 6 other Medical Specialists are ready to help you

JustAnswer in the News:

 
 
 
Ask-a-doc Web sites: If you've got a quick question, you can try to get an answer from sites that say they have various specialists on hand to give quick answers... Justanswer.com.
JustAnswer.com...has seen a spike since October in legal questions from readers about layoffs, unemployment and severance.
Web sites like justanswer.com/legal
...leave nothing to chance.
Traffic on JustAnswer rose 14 percent...and had nearly 400,000 page views in 30 days...inquiries related to stress, high blood pressure, drinking and heart pain jumped 33 percent.
Tory Johnson, GMA Workplace Contributor, discusses work-from-home jobs, such as JustAnswer in which verified Experts answer people’s questions.
I will tell you that...the things you have to go through to be an Expert are quite rigorous.
 
 
 

What Customers are Saying:

 
 
 
  • I feel so much better today, and upon further investigation believe that there is a chance that the responses I got saved me from a serious, even life threatening situation. I am very grateful to the experts who answered me. Susan O. USA
< Last | Next >
  • I feel so much better today, and upon further investigation believe that there is a chance that the responses I got saved me from a serious, even life threatening situation. I am very grateful to the experts who answered me. Susan O. USA
  • I can go as far as to say it could have resulted in saving my sons life and our entire family now knows what bipolar is and how to assist and understand my most wonderful son, brother and friend to all who loves him dearly. Thank you very much Corrie Moll Pretoria, South Africa
  • I thank-you so much! It really helped to have this information and confirmation. We will watch her carefully and get her in for the examination and US right away if things do not improve. God bless you as well! Claudia Albuquerque, NM
  • Outstanding response time less than 6 minutes. Answered the question professionally and with a great deal of compassion. Kevin Beaverton, OR
  • Suggested diagnosis was what I hoped and will take this info to my doctor's appointment next week.
    I feel better already! Thank you.
    Elanor Tracy, CA
  • Thank you to the Physician who answered my question today. The answer was far more informative than what I got from the Physicians I saw in person for my problem. Julie Lockesburg, AR
  • You have been more help than you know. I seriously don't know what my sisters situation would be today if you had not gone above and beyond just answering my questions. John and Stefanie Tucson, AZ
 
 
 

Meet The Experts:

 
 
 
  • Dr. Thomas, MD

    Board Certified Physician

    Satisfied Customers:

    46349
    Internal Medicine--practice all of internal medicine, all ages, family, also Integrative, CAM, etc
< Last | Next >
  • http://ww2.justanswer.com/uploads/DR/DrThomasMd/2012-7-25_134438_Imagess1.64x64.jpg Dr. Thomas, MD's Avatar

    Dr. Thomas, MD

    Board Certified Physician

    Satisfied Customers:

    46349
    Internal Medicine--practice all of internal medicine, all ages, family, also Integrative, CAM, etc
  • http://ww2.justanswer.com/uploads/MY/mysticdoc/2012-6-8_15615_mysticdoc3.64x64.jpg Dr. D.J.'s Avatar

    Dr. D.J.

    Board Certified Physician

    Satisfied Customers:

    14679
    MD
  • http://ww2.justanswer.com/uploads/agketch/2008-7-14_184046_drketchresized.jpg Dr. Ketch's Avatar

    Dr. Ketch

    Board Certified Physician

    Satisfied Customers:

    76
    Medical Degree, Former Assistant Professor at School of Medicine at Yale University
  • http://ww2.justanswer.com/uploads/FA/FamilyPhysician/2013-8-31_191624_JA550x500Photo.64x64.jpg Family Physician's Avatar

    Family Physician

    Doctor

    Satisfied Customers:

    2562
    Emergency Medicine and Family Practice for over 26 years
  • http://ww2.justanswer.com/uploads/DR/drappapo/2013-8-16_22576_drdavid.64x64.jpg Dr. David's Avatar

    Dr. David

    Board Certified Physician

    Satisfied Customers:

    224
    Treat children/young adults, former chief resident, multiple publications
  • http://ww2.justanswer.com/uploads/DrDLove/2009-08-12_141522_DrDLove.jpg Dr. D. Love's Avatar

    Dr. D. Love

    Doctor

    Satisfied Customers:

    11961
    Family Physician for 10 years; Hospital Medical Director for 10 years.
  • http://ww2.justanswer.com/uploads/CO/commissure/2011-4-15_192514_REISD20080926JR1090.64x64.jpg Dr. David's Avatar

    Dr. David

    Board Certified Physician

    Satisfied Customers:

    10667
    Experienced Physician trained in New York City. I'm ready to help.
 
 
 

Related Medical Questions

Chat Now With A Doctor
Dr. Owen
Dr. Owen
8537 Satisfied Customers
Board Certified in 2 Specialities & US Medical Graduate