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Family Physician
Family Physician, Doctor
Category: Medical
Satisfied Customers: 12816
Experience:  Emergency Medicine and Family Practice for over 26 years
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Does Diclofenac show up in a drug screen test

Customer Question

Does Diclofenac show up in a drug screen test?
Submitted: 6 years ago.
Category: Medical
Expert:  Dr. D. Love replied 6 years ago.

The usual drug screen that is done for drugs of abuse does not look for diclofenac. The diclofenac is metabolized and the metabolite is excreted in the urine, so a specific test can be done to look for it, but that is not typically done.


Expert:  Family Physician replied 6 years ago.
Dr. Love's answer is indeed correct. I do want to one particular point.

Diclofenac is a non-steroidal antiinflammatory medications (NSAID). This class of medications can cause FALSE POSITIVE screening tests for marijuana.

Additional testing using a confirmation test (GC/MS) would determine that this was a false positive, and not a true positive.

Please accept Dr. Love's answer. I added this answer for clarification.
Customer: replied 6 years ago.
Is there anything in the excreted metabolite that would show up as a barbituate, or any kind of a sedative type drug.
Expert:  Family Physician replied 6 years ago.
There are no published reports of this medication causing a false positive for barbiturate or the benzodiazepines ("sedative"), although a different member of the class can cause false positives for benzodiazepines.

Again - this would ONLY cause a false positive on the screening, and not on the GC/MS confirmed definitive testing.