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Family Physician
Family Physician, Doctor
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Experience:  Emergency Medicine and Family Practice for over 26 years
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What is the difference between Glipizide and Metformin. My

Resolved Question:

What is the difference between Glipizide and Metformin. My husband and I both have type 2 diabetes but one doctor prescribes metformin and the other glipizide?
Submitted: 6 years ago.
Category: Medical
Expert:  Family Physician replied 6 years ago.
Glipizide and metformin are both excellent medications used to treat diabetes.

Glipizide works to increase release of insulin from the pancreas, while metformin improves the sensitivity of the cells in the body to the effects of insulin.

There isn't one "right" or "wrong" answer to the question; "Which is the best medication for diabetes?" The choice depends on physician preference, differences in patient's medical condition(s), and response to treatments.
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