How JustAnswer Works:

  • Ask an Expert
    Experts are full of valuable knowledge and are ready to help with any question. Credentials confirmed by a Fortune 500 verification firm.
  • Get a Professional Answer
    Via email, text message, or notification as you wait on our site.
    Ask follow up questions if you need to.
  • 100% Satisfaction Guarantee
    Rate the answer you receive.

Ask Dr. Abid Your Own Question

Dr. Abid
Dr. Abid, Doctor
Category: Medical
Satisfied Customers: 3996
Experience:  MBBS, FCPS(R)
Type Your Medical Question Here...
Dr. Abid is online now
A new question is answered every 9 seconds

My brother has a white blood cell count of 17,000. He has

Customer Question

My brother has a white blood cell count of 17,000. He has been tested for all cancers, including a bone marrow test and all have come back negative. He is negative for Rheumatiod arthritis and Diabetes. My sister- in-law and I have been trying to get an idea of what could be wrong with him and have been unable to identify anything to help. The doctors are stumped. What can we do? Where can we go to get an answer?
Submitted: 4 years ago.
Category: Medical
Expert:  Dr. Abid replied 4 years ago.

please tell me that whether he has any history of fever,weight loss,or infection of any area?

what is the percentage of neutrophils and lymphocytes in blood complete picture?

Regards.

Customer: replied 4 years ago.
He has had no history of fever, weight loss, or infections. He does say that he sometimes gets disoriented, for instance, he went into Wal-Mart to get some things and could not remember where he was, what he was doing there or how to leave. It really scared him. After an hour of just walking around, he left and went home. He gets tired, dizzy, and just generally feels bad. But, it is not all the time. Sometimes he feels really good. His WBC count started out around 13,000. It has continued to go up, the latest count was 17,000 this past week. He has been dealing with this for over a year now. I will try to get the information regarding his neutrophils and lymphocytes, but it may be after he gets home form work this evening. Thank you.
Expert:  Dr. Abid replied 4 years ago.

yes please when you get information regarding his neutrophils and lymphocytes then you can reply so that i may proceed further accordingly.

Regards.

Customer: replied 4 years ago.

Dr. Abid

 

I just got the info you requested this morning. These are the average of 6 blood draws from 4/09 to 8/09. His last test was 1/1/10 and his "count" was 16.6 (I'm assuming that is Neutrophils gran)

Neutrophil % 67, Lymphocytes % 24, Monocytes % 8. Neutrophils (gran) 10, Lymphocytes:3.4, Monocytes 1.0.

MPV 7.0

JAK2 Mutation, Leumeta: negative

JAK2 V617F Mutation detection (NOTE) there was nothing else after that.

All that follows is from the bone biopsy results on 7/22/09

Clinical history of Leukocytosis

Microscopic Description: Specimens reviewed-peripheral blood, FE, TP and decalcified trephine biopsy. The peripheral blood smear shows borderline leukocytosis composed predomiantly of neutrophils. A rare circulating myelocyte is seen but there is no significant left shift or basophilia. Red cells and platelets are normal. Bone marrow shows a cellularity of 20-30%. Magakaryocytes are present and adequate. Erythroid and granulocytic precursors show complete maturation. No metastatic tumor. No lymphoma/lymphiod aggregates. No granulomas. Bony trabeculae are unremarkable.

COMMENT: Due to the lack of aspirate and quality of touch prep, maturation cannot be fully assessed. However, the biopsy shows complete maturation of both erythroid and myeloid elements with no abnormal localization or clusters or blasts.

 

I hope this helps. Thank you.

Expert:  Dr. Abid replied 4 years ago.

thanks for a nice info as his problem is just neutrophilic leucocytosis rest of his parameters are with in normal range,his workup fo jak 2 mutations are negative,good maturation of other cells in bone marrow biopsy with no evidence of any blood cancer and no evidence of infection is highly encouraging and good news :) now we have to sort out the cause of neutrophilic leucocytosis The most common and important cause of neutrophilia is infection, and most infections cause neutrophilia but in this case no evidence of infection seen so this is highly unlikely.Tissue damage from other causes raises the white count for similar reasons. Burns, infarction (cutting off the blood supply to a region of the body so that it dies), crush injuries, inflammatory diseases, poisonings, and severe diseases, all cause neutrophilia.Drugs can also cause leukocytosis. Cortisone-like drugs (prednisone), lithium, and NSAIDs are the most common offenders

here i want to share important,last but not leaset cause of neutrophilic leucocytosis if no other cause found then it has been seen thtan non-specific stresses also cause white blood cells to increase in the blood.and they concluded this fact by extensive testing of medical students reveals that neutrophilia accompanies every examination. Vigorous exercise and intense excitement also cause elevated white blood cell counts.so if even no other medical cause can be found than we should think of these some conditions.

Regards.

Customer: replied 4 years ago.
He is not an exerciser. He has had severe stress, divorce in the last two years and has remarried in September. Are those the stresses you are referring to? He works on a light bulb making factory around mercury. Could this have anything to do with his elevated neutrophils? He also has high blood pressure and high cholesterol and takes medication for those issues.
Expert:  Dr. Abid replied 4 years ago.

Yes as i mentioned stress can result in to elevated white blood cell count as and acccrding to your statement he has quite stressful life,second in the background of high blood pressure high cholestrol level and stressful life he may need evaluation for heart disease as infarction(cutting of blood supply)can result in to neutrophilic leucocytosis.

 

Regards.

Dr. Abid, Doctor
Category: Medical
Satisfied Customers: 3996
Experience: MBBS, FCPS(R)
Dr. Abid and 10 other Medical Specialists are ready to help you
Customer: replied 4 years ago.
Thank you Dr. Abid. At least we have another area to explore. I truely appreciate you taking your time and knowledge to help my brother and me.
Expert:  Dr. Abid replied 4 years ago.

thankyou sir you are most wellcome :)

Regards.

JustAnswer in the News:

 
 
 
Ask-a-doc Web sites: If you've got a quick question, you can try to get an answer from sites that say they have various specialists on hand to give quick answers... Justanswer.com.
JustAnswer.com...has seen a spike since October in legal questions from readers about layoffs, unemployment and severance.
Web sites like justanswer.com/legal
...leave nothing to chance.
Traffic on JustAnswer rose 14 percent...and had nearly 400,000 page views in 30 days...inquiries related to stress, high blood pressure, drinking and heart pain jumped 33 percent.
Tory Johnson, GMA Workplace Contributor, discusses work-from-home jobs, such as JustAnswer in which verified Experts answer people’s questions.
I will tell you that...the things you have to go through to be an Expert are quite rigorous.
 
 
 

What Customers are Saying:

 
 
 
  • I feel so much better today, and upon further investigation believe that there is a chance that the responses I got saved me from a serious, even life threatening situation. I am very grateful to the experts who answered me. Susan O. USA
< Last | Next >
  • I feel so much better today, and upon further investigation believe that there is a chance that the responses I got saved me from a serious, even life threatening situation. I am very grateful to the experts who answered me. Susan O. USA
  • I can go as far as to say it could have resulted in saving my sons life and our entire family now knows what bipolar is and how to assist and understand my most wonderful son, brother and friend to all who loves him dearly. Thank you very much Corrie Moll Pretoria, South Africa
  • I thank-you so much! It really helped to have this information and confirmation. We will watch her carefully and get her in for the examination and US right away if things do not improve. God bless you as well! Claudia Albuquerque, NM
  • Outstanding response time less than 6 minutes. Answered the question professionally and with a great deal of compassion. Kevin Beaverton, OR
  • Suggested diagnosis was what I hoped and will take this info to my doctor's appointment next week.
    I feel better already! Thank you.
    Elanor Tracy, CA
  • Thank you to the Physician who answered my question today. The answer was far more informative than what I got from the Physicians I saw in person for my problem. Julie Lockesburg, AR
  • You have been more help than you know. I seriously don't know what my sisters situation would be today if you had not gone above and beyond just answering my questions. John and Stefanie Tucson, AZ
 
 
 

Meet The Experts:

 
 
 
  • Dr. Thomas, MD's Avatar

    Dr. Thomas, MD

    Board Certified Physician

    Satisfied Customers:

    44473
    Internal Medicine--practice all of internal medicine, all ages, family, also Integrative, CAM, etc
< Last | Next >
  • http://ww2.justanswer.com/uploads/DR/DrThomasMd/2012-7-25_134438_Imagess1.64x64.jpg Dr. Thomas, MD's Avatar

    Dr. Thomas, MD

    Board Certified Physician

    Satisfied Customers:

    44473
    Internal Medicine--practice all of internal medicine, all ages, family, also Integrative, CAM, etc
  • http://ww2.justanswer.com/uploads/MY/mysticdoc/2012-6-8_15615_mysticdoc3.64x64.jpg Dr. D.J.'s Avatar

    Dr. D.J.

    Board Certified Physician

    Satisfied Customers:

    13579
    MD
  • http://ww2.justanswer.com/uploads/agketch/2008-7-14_184046_drketchresized.jpg Dr. Ketch's Avatar

    Dr. Ketch

    Board Certified Physician

    Satisfied Customers:

    76
    Medical Degree, Former Assistant Professor at School of Medicine at Yale University
  • http://ww2.justanswer.com/uploads/FA/FamilyPhysician/2013-8-31_191624_JA550x500Photo.64x64.jpg Family Physician's Avatar

    Family Physician

    Doctor

    Satisfied Customers:

    2522
    Emergency Medicine and Family Practice for over 26 years
  • http://ww2.justanswer.com/uploads/DR/drappapo/2013-8-16_22576_drdavid.64x64.jpg Dr. David's Avatar

    Dr. David

    Board Certified Physician

    Satisfied Customers:

    224
    Treat children/young adults, former chief resident, multiple publications
  • http://ww2.justanswer.com/uploads/DrDLove/2009-08-12_141522_DrDLove.jpg Dr. D. Love's Avatar

    Dr. D. Love

    Doctor

    Satisfied Customers:

    11042
    Family Physician for 10 years; Hospital Medical Director for 10 years.
  • http://ww2.justanswer.com/uploads/DO/DoctorRich/2012-9-12_72454_Doctorweb.64x64.jpg Dr. Natasha's Avatar

    Dr. Natasha

    Doctor

    Satisfied Customers:

    8749
    American Board Certified in Emergency Medicine and Ivy League trained. Medical Review Officer trained in Drug Testing