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DO NOT cut the duragesic patches in half. As per the manufacturer of these patches, cutting the patch can alter the integrity of the delivery system and can lead to an overdose of the medication. Overdose of the medication can cause suppression of you breathing and it can kill you. You should also not take hydrocodone and fentanyl together as it can increase the amount of opioid in your circulation leading to CNS and respiratory depression. as well low blood pressure. The overdose can be potentially fatal.
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