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Chronic kidney disease (CKD) is when one suffers from gradual and usually permanent loss of kidney function over time. This happens gradually over time, usually months to years.
It is divided into five stages of increasing severity.
Stage 1 - Slight kidney damage with normal or increased filtration
Stage 2 - Mild decrease in kidney function
Stage 3 - Moderate decrease in kidney function
Stage 4 - Severe decrease in kidney function
Stage 5 - Kidney failure requiring dialysis or transplantation
GFR is the abbreviation for Glomerular Filtration Rate, it is the rate at which the kidneys can filter the blood off its waste products and unwanted substances that need to be excreated in the form of urine. It is about 30-59 mL/min/1.73(square) in stage 3 of CKD.
Stage 3 can be controlled by diet restriction, fluid restriction and some medicines and does not require hemodialysis or kidney transplant.
Hope this answers your query.
For a further read please view the following link:
Edited by Dr Uzair on 2/5/2010 at 7:51 PM EST