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The duration of action of a drug is known as its half life.
This is the period of time required for the concentration or amount of drug in the body to be reduced by one-half.
Half life of a drug is considered in relation to the amount of the drug in plasma.
Half life of hydrocodone is 3.8 hours.
Other component of hydrocodone-apap 10-325 is acetaminophen is 2-4 hours.
A drug's plasma half-life depends on how quickly the drug is eliminated from the plasma.
After leaving plasma, drug is either eliminated from body via kidneys,liver or metabolised in to inactive particles.
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