Welcome To JustAnswer!
My name is Dustin, And I am one of the Experts who will assist you today!
Good morning, I would like to start off with these two steps.. Hopefully this is enough to resolve the issue, but if this doesnt work, or if you get stuck and cant complete the steps, please send a reply so that I can continue to assist you.
To open Disk Utility, from the Applications folder, open Utilities, and then double-click the Disk Utility icon.
In the column on the left, click your startup disk.
Click the First Aid tab, and then click Repair Disk Permissions. Disk Utility will reset any files and folders with incorrect settings.
Step 2.. ( once step one completes and you see the small progress bar say it is done reparing permissions) http://support.microsoft.com/kb/969291
From that link.. We should perform steps 1, 3, and 4 .. But most especially step 4.. The data base repair is the main goal of this operation...
Once complete, let me know if your entourage is working again...
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If my answer did not work, please wait to rate the answer and also wait to accept and instead send me a reply so that I can continue to assist you as needed.