Lexus Troubleshooting Questions? Ask a Lexus Expert
Ignition coil # ***** needs to be inspected for a impregnated top from over heating, or any mouse activate near connector. If none is found then I recommend swapping coil to a different cylinder, clearing check engine light and seeing if the P1325 changes to indicate the other cylinder that coil #6 was swapped to. You may also have an underlying oxygen sensor/ or cat issue but its hard to tell till the misfire is resolved first. See picture below for coil location.
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