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Good morning. A person does not have to voluntarily do this unless in custody or under an order of the court, to comply and submit to it. If the person is a suspect in a crime, the police can seek an arrest warrant and take them into custody and take a swab, to determine if they are linked to the alleged crime. However, the person does not have to voluntarily submit to one and can refuse one as well, if they desire. Here is also a link that shares examples of how the 4th amendment applies as well.
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If the person was of interest and considered a suspect in a crime, in which a DNA sample is needed. The burden would be on the State to present evidence and show why this is at issue and why they think this person was involved, for the Judge to order it.
Yes, at this time I could not see any reason for a DNA sample. If they were arrested, they were printed and they could just run the prints.
No, they would not. The reason being is that they were arrested and charged and the Judge has the legal ability to order submission to a DNA test. Their 4th amendment right would not be violated if the State could show and present evidence as to the basis for this swab.