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Yes, you just need to have a strong waiver of claims clause in what they sign. They need to understand the inherent risk in an experimental treatment. They also need to understand that they will not be covered under most standard insurance policies. You can add language that says you will provide reasonable assistance to the patient if they were to attempt to solicit preapproval from their insurance company, but payment will ultimately be patient's responsibility.
If you have any additional questions just let me know otherwise a positive rating would be greatly appreciated.