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I am sorry to hear about this situation. The answer is yes, you can will your entire estate to them, and no, your siblings cannot contest.
It is the surviving spouse that can often take a share of the estate even if they are left out of the Will, per something called an "elective share." Siblings do not have this right. This means that you can leave out your brothers/sisters from the Will, and leave your estate to whomever you want to. They would not be able to contest.
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