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HelloThis is Samuel and I will discuss this and provide you information in this regard.
453.31 Controlled Substances
If the distribution of a controlled substance is unlawful under 21 U.S.C. 801 or any implementing regulation in 21 CFR 1300, then the mailing of the substance is also unlawful under 18 U.S.C. 1716.
Controlled substances and drugs that contain controlled substances are acceptable in the domestic mail only under the following conditions:
In essence, it would be illegal for your sister to mail the medication. I suggest that if the pharmacy where the prescription was filled is the same in your/her area, that you discuss this with your pharmacist and they can help to have the local one in your sister's area mail it to you as they are registered.