Once the judgment is final, that is a debt against you that can be enforced with judicial means (levies, garnishments, till taps, etc.). This makes working around it difficult and gives the judgment creditor
the upper hand.
Your options (outside of an appeal) would include primarily working with the creditor to arrive at a payment plan or settlement that allows you to stay in business, but gives the creditor some payment. You can settle with them for whatever is deemed mutually acceptable, and courts generally encourage settlement, even post judgment.
If you cannot pay your debt, and the creditor refuses to work with you, you will need to consider insolvency
options, primarily bankruptcy or looking at the form of your company (are you an LLC or a corporation). I would recommend speaking with a bankruptcy or insolvency attorney to plan a bankruptcy if this appears to be your option as far in advance as possible as you will be able to maximize the benefit of such a judicial process. In the meantime, a bankruptcy or insolvency attorney is usually the best person to assist you in dealing with proportionally large debts as they can assist in the negotiations I referenced earlier.
There may be other options available to you specifically, but these are the general routes available to resolve large debts for businesses that cannot service them.