Penicillin should be given twice daily (at 12-hour intervals) for 3 days.
What is the name of the penicillin on the label? Is it Procaine penicillin G or Benzathine penicillin?
The concentration of Penicillin G Procaine is generally 300,000 units per mL (check the label).
The dosage is 10,000 units per pound.
4 mL given every 12 hours is the recommended dosage for a calf weighing between 100 and 125 pounds.
You can measure the success by taking the rectal temperature of the calf in the morning and evening. Normal temperature is 99.5 to 102.
If your calf has an elevated temperature or is still coughing after 3 days, switch to ceftiofur (Naxcel or Excenel).