Hi Nick. My name is***** you for your question and the opportunity to assist.
How long ago did this start?
System Restore may get this working.
With the computer started up in Safe Mode hold down the Windows logo key (just to the left of the spacebar) and press R.
The Run box will open.
In the text box type: rstrui.exe and click OK.
When System Restore starts click Next.
Put a checkmark in the Show more restore points box (if available)
Select a restore date when the USB ports were working and click Next.
Click Finish and allow the restore to complete.
After the computer restarts check that the USB ports are now working.
Let me know the result please.
This will not affect your files or programs.
Hi. If System Restore didn't resolve the issue there are more possible solutions. Those machines came with either Win 7 or 8 and were also touchscreen or non-touchscreen. For the sake of this response I'm assuming you have a non-touch machine running Windows 7.
Something running on the machine is keeping the USB drivers from running when it's started normally. The fact the the ports are working in Safe Mode indicates that. We can try turning off what starts when Windows does and see if the drivers will work in normal mode.
Click Start and in the search area type: msconfig and click OK. In the System Configuration window select the Startup tab.
Click Disable All and then click Apply.
Click the Services tab. Put a checkmark in the Hide All Microsoft Services box. Then click Disable All > Apply > OK
You'll then restart the machine but before doing that make sure the only USB device plugged in to a port is the receiver
for the keyboard/mouse.
Check that when it starts up normally the ports work.
Thanks Nick. Do you use any kind of driver updater program on the computer?
Something that is supposed to scan your machine and check for updated drivers?
A non-Windows product.
Thanks. There's something going on with the USB drivers.
Can you start the machine in Safe Mode with Networking
so that you'll have internet access. If you can,
click Start and in the search area type: device manager and open the search result at the top
Expand the entry for USB Serial Bus Controllers.
Right click on every item and have Windows search for updated drivers.
Do you have any Samsung (Kies) software installed on the machine?
Here's a link to the HP driver page for what I think is your model
In the Driver-Chipset section it's showing an updated USB driver
for 64 bit Windows 7 that came out last month.