Immigration Law Questions? Ask an Immigration Lawyer.
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I assume you mean that your nephew wants to study in college in USA. If so, then yes he can, although you do not actually do anything - he does. He applies for admission at a school and then also applies for the visa. He would need an F1 visa - see HERE.
You can see the steps to take to get an F1 visa HERE.
If there is a certain school he wishes to go to, then that school's INTERNATIONAL STUDENT OFFICE will often work with him to handle the application and immigration paperwork.
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