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does it have power door locks?
explain to me what is going on
Does the key turn in the drivers door lock at all? When you operate the power lock button inside the car do any of the locks work?
Sounds like you may have a bad door latch and actuator in the drivers door. If the drivers door lock does not work the others will not work either. the spin sound may be the stripped gears in the actuator.
That would depend on your level of experience. If you replace the lock cylinder you will have a different key to unlock that door with unless you have the dealer or locksmith re key it. Removing the door latch could be tricky, if you are not careful you can break the outer door handle.