Smoothed models of what?
Are these signal spectra? Are they images in the spatial (as opposed to sequency) domain?
I need a bit more detail before I can respond in a semantically meaningful manner.
Of course, this is more of an electrical engineering question, so to speak: the MATERIAL is electrical engineering, while the TOOL (Python) is an obvious component of the mature engineer's toolbox. We don't place languages on pedestals, as programmers are wont to do: a programming language is just a tool for characterizing a problem and using the raw power of Ye Olde Computerre to solve it.
Of course, I'm an electrical engineer, which helps.
Do me a tremendous favor:
Copy the text of questions 5 and 6 and plant them physically into the "Messages" stream of this Request.
That's the mechanism whereby we OFFICIALLY agree to a change of scope.
One of these days, I will figure out why Python has become so popular. It has numerous grievous issues. In fact, take a look at this paper, which I wrote some years ago. I apologize if you have difficulty following all of it, which I expect you will.