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1. Which of the following is a component of adaptive immunity? A.

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1. Which of the following is a component of adaptive immunity?
A. Lysozymes C. Hydrochloric acid
B. Skin D. Complement

2. The production of specific antibody is referred to as
A. cellular immunity. C. autoimmunity.
B. nonadaptive immunity. D. humoral immunity.

3. Which of the following is the most abundant circulating
immunoglobulin?
A. IgG C. IgM
B. IgD D. IgE

4. Which of the following is an antigen-antibody reaction that
results in the formation of insoluble particles?
A. ELISA C. Opsonization
B. Colloidal gold D. Precipitation

5. The procedure for a major cross-matching of blood involves incubation of which of the
following?
A. Recipient serum with recipient cells
B. Donor serum with donor cells
C. Recipient serum with donor serum
D. Recipient serum with donor cells

6. The solid phase of an ELISA test contains which of the following?
A. Chromagen C. An enzyme
B. An antibody D. A control

7. Which of the following is a condition characterized by the production of antibody
against the body’s own tissues?
A. Adaptive immunity C. Autoimmunity
B. Nonadaptive immunity D. Humoral immunity

8. Which leukocytes are responsible for synthesis and secretion of specific antibodies?
A. B-lymphocytes C. Macrophages
B. Neutrophils D. T-lymphocytes

9. Which of the following is an antigen-antibody reaction that increases an antigen’s
susceptibility to phagocytosis?
A. ELISA C. Opsonization
B. Colloidal gold D. Precipitation

10. Which immunoglobulin is associated with hypersensitivity reactions?
A. IgE C. IgM
B. IgG D. IgD

11. Which of the following is an example of a Type II hypersensitivity reaction?
A. Contact dermatitis
B. Autoimmune hemolytic anemia
C. Glomerulonephritis
D. Anaphylactic shock

12. Which of the following is an example of a Type I hypersensitivity reaction?
A. Contact dermatitis
B. Autoimmune hemolytic anemia
C. Glomerulonephritis
D. Anaphylactic shock

13. A substance capable of generating a response from the immune system is referred to
as a(n)
A. antibody. C. natural killer cell.
B. antigen. D. complement.

14. Receipt of maternal antibodies in colostrums is a type of _______ immunity.
A. passive C. cell-mediated
B. active D. humoral

15. Tests for diagnosis of brucellosis usually use the _______ method.
A. CELISA C. radioimmunoassay
B. ELISA D. latex agglutination

16. The Coombs test utilizes which of the following methods?
A. ELISA C. Agglutination
B. Precipitation D. Intradermal

17. Which of the following uses serial dilutions of a serum sample to detect levels of
circulating antibodies in the serum?
A. Fluorescent antibody C. RIM
B. Titer D. CELISA

18. The most serious transfusion reactions in dogs occur with the use of which canine
blood group subtype?
A. DEA1.1 C. Z
B. DEA7 D. AB

19. Which of the following tests measure a cell-mediated immune reaction?
A. Coombs C. Tuberculin skin test
B. ELISA D. RIM

20. Which complement pathway is activated by the binding of C1 to an antigen-antibody
complex?
A. Classical C. Chemotactic
B. Cascade D. Alternate

21. Which components of the immune system are involved in cell-mediated immunity?
A. B-lymphocytes C. Immunoglobulins
B. T-lymphocytes D. Plasma cells

22. Which of the following is the most accurate statement about antibody titers?
A. Results are reported as either positive or negative.
B. The higher the dilution, the more antibody there is in the sample.
C. A single, high-dilution titer (1:160 or above) indicates an active infection.
D. The higher the dilution, the harder the immunologist has to look to find antibody in
the sample.

23. An attenuated vaccine is one in which the microorganisms have been
A. removed. C. weakened.
B. killed. D. left unchanged.

24. Which of the following is normally used to diagnose equine infectious anemia?
A. ELISA C. Fluorescent antibody
B. Latex agglutination D. Immunodiffusion

25. The ability of the immune system to distinguish between self-antigens and foreign antigens
is referred to as
A. immunologic tolerance. C. apoptosis.
B. cell-mediated immunity. D. humoral immunity.
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