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There are no studies of phosphatidyl serine with serotonin or serotonin-norepinephrine reuptake inhibitors. It is known, however, that it can interfere with some medications including anti-inflammatories and blood thinners. Since it is thought to improve brain messaging, the side effects you are having may be from it increasing the effects of your Prozac and Effexor. Generally your body becomes accustomed to this in a week or two of use. If it continues beyond that, you may need to consider stopping the PS100 or asking your psychiatrist to reduce the dosages of your other drugs.
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